Seminole, last Native American tribe to make peace with the U.S. government. Seminole formed in Florida out of an alliance including refugee Creek from Georgia, native Apalachee and runaway slaves. They fought Andrew Jackson's troops in 1817–18 while Florida was still a Spanish territory. The major Seminole War began in 1835 when the U.S. government ordered their removal to west of the Mississippi. A fierce guerrilla war against overwhelming odds ended in 1842, after which most Seminoles were moved to Oklahoma. However, a small band held out in the Everglades until 1934, when they agreed to a settlement.