Gehrig, Lou (Henry Louis Gehrig; 1903–41), U.S. baseball player. As first baseman for the New York Yankees (1923–39) he set a record by playing 2,130 consecutive games. He had a .361 batting average in 7 world series, a lifetime average of .341, and 493 home runs. He died of a rare muscle-wasting disease, amyotrophic lateral sclerosis, called Lou Gehrig's disease. Gehrig was inducted into the National Baseball Hall of Fame in 1939.