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Cirrhosis, chronic disease of the liver marked by progressive destruction and regeneration of liver cells and increased connective tissue (scar) formation. Cirrhosis ultimately results in blockage of portal circulation, raised blood pressure in the portal vein, liver failure, and death. Causes include alcohol consumption (Laennec's cirrhosis, the most prevalent), hepatitis and other infections, and severe malnutrition in children of tropical countries (a condition known as kwashiorkor). Results include jaundice, gastrointestinal problems, and edema. Though irreparable, treatment includes vitamin intake, controlled diet, and diuretics.

See also: Liver.

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